https://ideawaza.com/api.php?action=feedcontributions&feedformat=atom&user=131.243.56.0%2F24IdeaWazaWiki - User contributions [en]2026-09-29T17:03:37ZUser contributionsMediaWiki 1.46.0https://ideawaza.com/index.php?title=Kr%C3%BCppel&diff=15675Krüppel2007-06-29T23:32:06Z<p>131.243.56.64: Corrected description of the image linked to.</p>
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<div>'''Krüppel''' is a [[gap gene]] which encodes a [[zinc finger]] protein with four tandemly repeated zinc finger domains.<ref>{{OMIM|165220}}</ref><br />
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Krüppel means, literally, "cripple" in German.<br />
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Put into English, it controls the development of a zygote early on in its growth, causing a gap in the otherwise [[heterogeneous]] arrangement of cells. It also controls access to several other subsequent genes, imposing order on the developing embryo.<ref>http://www.flybase.org/allied-data/lk/interactive-fly/segment/kruppel1.htm</ref> <br />
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See also [[Kruppel-like factors]] which have been recently investigated in the heart but are well characterised for their role in carcinogenesis.<br />
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==External links==<br />
* [http://www.bio.davidson.edu/courses/MolBio/fly/embryred.jpeg Diagram] at [[Davidson College]] - a Drosophila embryo at the cellular blastoderm stage triple-labeled for three segmentation proteins including Krüppel (in blue) Hairy (green) and Giant (red).<br />
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==References==<br />
<references/><br />
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==External links==<br />
* {{MeshName|Kruppel+protein,+Drosophila}}<br />
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[[Category:Genetics]]<br />
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{{genetics-stub}}</div>131.243.56.64https://ideawaza.com/index.php?title=Kr%C3%BCppel&diff=15674Krüppel2007-06-29T23:27:22Z<p>131.243.56.64: Removed superfluous word.</p>
<hr />
<div>'''Krüppel''' is a [[gap gene]] which encodes a [[zinc finger]] protein with four tandemly repeated zinc finger domains.<ref>{{OMIM|165220}}</ref><br />
<br />
Krüppel means, literally, "cripple" in German.<br />
<br />
Put into English, it controls the development of a zygote early on in its growth, causing a gap in the otherwise [[heterogeneous]] arrangement of cells. It also controls access to several other subsequent genes, imposing order on the developing embryo.<ref>http://www.flybase.org/allied-data/lk/interactive-fly/segment/kruppel1.htm</ref> <br />
<br />
See also [[Kruppel-like factors]] which have been recently investigated in the heart but are well characterised for their role in carcinogenesis.<br />
<br />
==External links==<br />
* [http://www.bio.davidson.edu/courses/MolBio/fly/embryred.jpeg Diagram] at [[Davidson College]] - a Drosophila embryo at the cellular blastoderm stage triple-labeled for three segmentation proteins including Kruppel (green) Hairy (red) and Giant (in blue)<br />
<br />
==References==<br />
<references/><br />
<br />
==External links==<br />
* {{MeshName|Kruppel+protein,+Drosophila}}<br />
<br />
[[Category:Genetics]]<br />
<br />
<br />
{{genetics-stub}}</div>131.243.56.64