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		<id>https://ideawaza.com/index.php?title=Archive:Total_parenteral_nutrition&amp;diff=30165</id>
		<title>Archive:Total parenteral nutrition</title>
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		<updated>2005-09-30T14:47:12Z</updated>

		<summary type="html">&lt;p&gt;64.4.116.187: Corrected small grammatical mistake&lt;/p&gt;
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&lt;div&gt;&#039;&#039;&#039;Total parenteral nutrition&#039;&#039;&#039; (TPN), also called [[hyperalimentation]], is the practice of feeding a person without using the [[gut]], i.e. intravenously.  It is normally used during [[surgery|surgical]] recoveries.  It has been used for patients in [[coma]], although enteric (tube) feeding is usually preferable, and less prone to complications.  [[Chronic]] TPN is occasionally used to treat people suffering the extended consequences of an accident or surgery.  Most controversially, TPN has extended the life of a small number of children born with nonexistent or severely birth-deformed guts.  The oldest were eight years old in [[2003]].&lt;br /&gt;
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In TPN&#039;s simplest form, a bag of [[nutrient]]s is added to a patient&#039;s [[intravenous drip]].&lt;br /&gt;
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The preferred method of performing TPN is with a medical [[infusion pump]].  A [[sterile]] bag of nutrient solution, between 500mL and 4L is provided.  The pump infuses a small amount (0.1 to 10mL/hr) continuously in order to keep the vein open.  Feeding schedules vary, but one common regimen ramps up the nutrition over a few hours, levels off the rate for a few hours, and then ramps it down over a few more hours, in order to simulate a normal set of meal times.&lt;br /&gt;
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The nutrient solution consists of [[water]], [[glucose]], [[salt]]s, [[amino acid]]s, [[vitamin]]s and (more controversially) sometimes emulsified [[fat]]s.  Long term TPN patients sometimes suffer from lack of trace nutrients or [[electrolyte]] imbalances.  Because increased [[blood sugar]] commonly occurs  with TPN, [[insulin]] may also be added to the infusion.  Occasionally, other drugs are added as well. &lt;br /&gt;
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Chronic TPN is performed through a [[Hickman line]] or a [[Port-a-Cath]] (venous access systems), or sometimes through an [[artery]]. Arterial shunts are more dangerous, but sturdier because an artery wall is more muscular. Poor [[hygiene]] may lead to serious [[infection]].&lt;br /&gt;
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Battery-powered ambulatory infusion pumps are used with chronic TPN patients, and usually the pump and a small (100ml) bag of nutrient to keep the vein open are carried in a fanny pack.  Outpatient TPN practices are still being refined.&lt;br /&gt;
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Aside from their dependence on a pump, chronic TPN patients live quite normal lives.&lt;br /&gt;
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==Complications==&lt;br /&gt;
There are some complications that seem to follow long-term use of TPN.  The most common is [[liver]] failure.  [[As of 2004]], the cause is unknown, but may be insufficient nutrition - the liver normally processes the [[blood]] returning from the gut.&lt;br /&gt;
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==See also==&lt;br /&gt;
* [[intravenous drip]]&lt;br /&gt;
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[[Category:nutrition]]&lt;br /&gt;
[[Category:intensive care medicine]]&lt;br /&gt;
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[[de:Parenterale Ernährung]]&lt;br /&gt;
[[pt:Nutrição parenteral]]&lt;/div&gt;</summary>
		<author><name>64.4.116.187</name></author>
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