Krüppel: Difference between revisions
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'''Krüppel''' is a | '''Krüppel''' is a gap gene which encodes a zinc finger protein with four tandemly repeated zinc finger domains. | ||
Krüppel means, literally, "cripple" in German. | Krüppel means, literally, "cripple" in German. | ||
Put into English, it controls the development of a zygote early on in its growth, causing a gap in the otherwise | Put into English, it controls the development of a zygote early on in its growth, causing a gap in the otherwise heterogeneous arrangement of cells. It also controls access to several other subsequent genes, imposing order on the developing embryo. | ||
See also | See also Kruppel-like factors which have been recently investigated in the heart but are well characterised for their role in carcinogenesis. | ||
==External links== | ==External links== | ||
* [http://www.bio.davidson.edu/courses/MolBio/fly/embryred.jpeg Diagram] at [[Davidson College]] - a Drosophila embryo at the cellular blastoderm stage triple-labeled for three segmentation proteins including Krüppel (in blue) Hairy (green) and Giant (red). | * [http://www.bio.davidson.edu/courses/MolBio/fly/embryred.jpeg Diagram] at [[Davidson College]] - a Drosophila embryo at the cellular blastoderm stage triple-labeled for three segmentation proteins including Krüppel (in blue) Hairy (green) and Giant (red). | ||
* {{MeshName|Kruppel+protein,+Drosophila}} | * {{MeshName|Kruppel+protein,+Drosophila}} | ||
[[Category:Genetics]] | [[Category:Genetics]] | ||
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Latest revision as of 18:06, 11 April 2009
Krüppel is a gap gene which encodes a zinc finger protein with four tandemly repeated zinc finger domains.
Krüppel means, literally, "cripple" in German.
Put into English, it controls the development of a zygote early on in its growth, causing a gap in the otherwise heterogeneous arrangement of cells. It also controls access to several other subsequent genes, imposing order on the developing embryo.
See also Kruppel-like factors which have been recently investigated in the heart but are well characterised for their role in carcinogenesis.
External links
- Diagram at Davidson College - a Drosophila embryo at the cellular blastoderm stage triple-labeled for three segmentation proteins including Krüppel (in blue) Hairy (green) and Giant (red).
