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Alpha:VDAC2: Difference between revisions

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{{protein
| name = voltage-dependent anion channel 2
| caption =
| image =
| width =
| HGNCid = 12672
| Symbol = VDAC2
| AltSymbols =
| EntrezGene = 7417
| OMIM = 193245
| RefSeq = NM_003375
| UniProt = P45880
| PDB =
| ECnumber =
| Chromosome = 10
| Arm = q
| Band = 22
| LocusSupplementaryData =
}}
'''Voltage-dependent anion channel 2''', also known as '''VDAC2''', is a human [[gene]]. The [[protein]] encoded by this gene is a [[voltage-dependent anion channel]].<ref name="pmid7517385">{{cite journal | author = Blachly-Dyson E, Baldini A, Litt M, McCabe ER, Forte M | title = Human genes encoding the voltage-dependent anion channel (VDAC) of the outer mitochondrial membrane: mapping and identification of two new isoforms | journal = Genomics | volume = 20 | issue = 1 | pages = 62–7 | year = 1994 | month = March | pmid = 7517385 | doi = 10.1006/geno.1994.1127 | url = | issn = }}</ref><ref name="pmid10049775">{{cite journal | author = Messina A, Oliva M, Rosato C, Huizing M, Ruitenbeek W, van den Heuvel LP, Forte M, Rocchi M, De Pinto V | title = Mapping of the human Voltage-Dependent Anion Channel isoforms 1 and 2 reconsidered | journal = Biochem. Biophys. Res. Commun. | volume = 255 | issue = 3 | pages = 707–10 | year = 1999 | month = February | pmid = 10049775 | doi = 10.1006/bbrc.1998.0136 | url = | issn = }}</ref>
'''Voltage-dependent anion channel 2''', also known as '''VDAC2''', is a human [[gene]]. The [[protein]] encoded by this gene is a [[voltage-dependent anion channel]].<ref name="pmid7517385">{{cite journal | author = Blachly-Dyson E, Baldini A, Litt M, McCabe ER, Forte M | title = Human genes encoding the voltage-dependent anion channel (VDAC) of the outer mitochondrial membrane: mapping and identification of two new isoforms | journal = Genomics | volume = 20 | issue = 1 | pages = 62–7 | year = 1994 | month = March | pmid = 7517385 | doi = 10.1006/geno.1994.1127 | url = | issn = }}</ref><ref name="pmid10049775">{{cite journal | author = Messina A, Oliva M, Rosato C, Huizing M, Ruitenbeek W, van den Heuvel LP, Forte M, Rocchi M, De Pinto V | title = Mapping of the human Voltage-Dependent Anion Channel isoforms 1 and 2 reconsidered | journal = Biochem. Biophys. Res. Commun. | volume = 255 | issue = 3 | pages = 707–10 | year = 1999 | month = February | pmid = 10049775 | doi = 10.1006/bbrc.1998.0136 | url = | issn = }}</ref>


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* {{MeshName|VDAC2+protein,+human}}
* {{MeshName|VDAC2+protein,+human}}


{{membrane-protein-stub}}
{{Ion channels}}
[[Category:Ion channels]]
[[Category:Ion channels]]

Revision as of 18:52, 25 March 2009

Voltage-dependent anion channel 2, also known as VDAC2, is a human gene. The protein encoded by this gene is a voltage-dependent anion channel.[1][2]

VDAC2 is involved in the regulation of mitochondrial apoptosis.[3]

References

  1. ↑ Blachly-Dyson E, Baldini A, Litt M, McCabe ER, Forte M (March 1994). "Human genes encoding the voltage-dependent anion channel (VDAC) of the outer mitochondrial membrane: mapping and identification of two new isoforms". Genomics 20 (1): 62–7. doi:10.1006/geno.1994.1127. PMID 7517385. 
  2. ↑ Messina A, Oliva M, Rosato C, Huizing M, Ruitenbeek W, van den Heuvel LP, Forte M, Rocchi M, De Pinto V (February 1999). "Mapping of the human Voltage-Dependent Anion Channel isoforms 1 and 2 reconsidered". Biochem. Biophys. Res. Commun. 255 (3): 707–10. doi:10.1006/bbrc.1998.0136. PMID 10049775. 
  3. ↑ Cheng EH, Sheiko TV, Fisher JK, Craigen WJ, Korsmeyer SJ (July 2003). "VDAC2 inhibits BAK activation and mitochondrial apoptosis". Science (journal) 301 (5632): 513–7. doi:10.1126/science.1083995. PMID 12881569.