Archive:Peptidein: Difference between revisions
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{{Short description|Small proteins in human}} | {{Short description|Small proteins in human}} | ||
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{{Article for deletion/dated|page=Peptidein|timestamp=20261024151326|year=2026|month=October|day=24|substed=yes|help=off|outcome=merging|target=Micropeptide}} | |||
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A '''peptidein''' is a small molecule made up of [[amino acids]] similar in appearance and biomechanical role to proteins.<ref name=":0">{{Cite journal |last=Callaway |first=Ewen |date=2026-05-06 |title=Revealed: the mysterious 'dark' proteins that might play a big role in biology |url=https://www.nature.com/articles/d41586-026-01492-x |journal=Nature |language=en |doi=10.1038/d41586-026-01492-x |pmid=42092205 |issn=1476-4687|url-access=subscription }}</ref> More than 1,700 types of peptideins have been identified, most of which are of unknown functions, but some are implicated with [[Genetic disorder|genetic diseases]] and [[cancer]].<ref>{{Cite web |last=Ktori |first=Sophia |date=2026-05-06 |title=Microproteins and Peptideins Expand Boundaries of the Human Proteome |url=https://www.genengnews.com/topics/omics/microproteins-and-peptideins-expand-boundaries-of-the-human-proteome/ |access-date=2026-05-08 |website=GEN - Genetic Engineering and Biotechnology News |language=en-US}}</ref> Popularly called the "dark [[proteome]]"<ref name=":2">{{Cite web |last=Smith |first=Rhianna-lily |date=2026-05-07 |title=The Human Proteome Just Got 10% Bigger |url=http://www.technologynetworks.com/tn/news/the-human-proteome-just-got-10-bigger-412414 |access-date=2026-05-08 |website=Technology Networks |language=en}}</ref> or "dark proteins"<ref name=":3">{{Cite journal |last=Callaway |first=Ewen |date=2025-01-29 |title='Dark proteins' hiding in our cells could hold clues to cancer and other diseases |url=https://www.nature.com/articles/d41586-025-00217-w |journal=Nature |language=en |volume=637 |issue=8048 |pages=1038–1040 |doi=10.1038/d41586-025-00217-w |pmid=39880991 |bibcode=2025Natur.637.1038C |issn=1476-4687|url-access=subscription }}</ref> due to their elusive identity, they are a type of [[microproteins]], and were identified by an international team of scientists led by Sebastiaan van Heesch of the Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands, in 2026.<ref>{{Cite web |last=Harley |first=Sadie |date=2026-05-06 |title=Dark proteome yields 1,785 new microproteins that could reshape disease research |url=https://phys.org/news/2026-05-dark-proteome-yields-microproteins-reshape.html |website=Phys.org}}</ref> | A '''peptidein''' is a small molecule made up of [[amino acids]] similar in appearance and biomechanical role to proteins.<ref name=":0">{{Cite journal |last=Callaway |first=Ewen |date=2026-05-06 |title=Revealed: the mysterious 'dark' proteins that might play a big role in biology |url=https://www.nature.com/articles/d41586-026-01492-x |journal=Nature |language=en |doi=10.1038/d41586-026-01492-x |pmid=42092205 |issn=1476-4687|url-access=subscription }}</ref> More than 1,700 types of peptideins have been identified, most of which are of unknown functions, but some are implicated with [[Genetic disorder|genetic diseases]] and [[cancer]].<ref>{{Cite web |last=Ktori |first=Sophia |date=2026-05-06 |title=Microproteins and Peptideins Expand Boundaries of the Human Proteome |url=https://www.genengnews.com/topics/omics/microproteins-and-peptideins-expand-boundaries-of-the-human-proteome/ |access-date=2026-05-08 |website=GEN - Genetic Engineering and Biotechnology News |language=en-US}}</ref> Popularly called the "dark [[proteome]]"<ref name=":2">{{Cite web |last=Smith |first=Rhianna-lily |date=2026-05-07 |title=The Human Proteome Just Got 10% Bigger |url=http://www.technologynetworks.com/tn/news/the-human-proteome-just-got-10-bigger-412414 |access-date=2026-05-08 |website=Technology Networks |language=en}}</ref> or "dark proteins"<ref name=":3">{{Cite journal |last=Callaway |first=Ewen |date=2025-01-29 |title='Dark proteins' hiding in our cells could hold clues to cancer and other diseases |url=https://www.nature.com/articles/d41586-025-00217-w |journal=Nature |language=en |volume=637 |issue=8048 |pages=1038–1040 |doi=10.1038/d41586-025-00217-w |pmid=39880991 |bibcode=2025Natur.637.1038C |issn=1476-4687|url-access=subscription }}</ref> due to their elusive identity, they are a type of [[microproteins]], and were identified by an international team of scientists led by Sebastiaan van Heesch of the Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands, in 2026.<ref>{{Cite web |last=Harley |first=Sadie |date=2026-05-06 |title=Dark proteome yields 1,785 new microproteins that could reshape disease research |url=https://phys.org/news/2026-05-dark-proteome-yields-microproteins-reshape.html |website=Phys.org}}</ref> | ||