Krüppel: Difference between revisions
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==External links== | ==External links== | ||
* [http://www.bio.davidson.edu/courses/MolBio/fly/embryred.jpeg Diagram] at [[Davidson College]] - a Drosophila embryo at the cellular blastoderm stage triple-labeled for three segmentation proteins including | * [http://www.bio.davidson.edu/courses/MolBio/fly/embryred.jpeg Diagram] at [[Davidson College]] - a Drosophila embryo at the cellular blastoderm stage triple-labeled for three segmentation proteins including Krüppel (in blue) Hairy (green) and Giant (red). | ||
==References== | ==References== | ||
Revision as of 23:32, 29 June 2007
Krüppel is a gap gene which encodes a zinc finger protein with four tandemly repeated zinc finger domains.[1]
Krüppel means, literally, "cripple" in German.
Put into English, it controls the development of a zygote early on in its growth, causing a gap in the otherwise heterogeneous arrangement of cells. It also controls access to several other subsequent genes, imposing order on the developing embryo.[2]
See also Kruppel-like factors which have been recently investigated in the heart but are well characterised for their role in carcinogenesis.
External links
- Diagram at Davidson College - a Drosophila embryo at the cellular blastoderm stage triple-labeled for three segmentation proteins including Krüppel (in blue) Hairy (green) and Giant (red).
References
External links
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