Krüppel: Difference between revisions
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Krüppel means, literally, "cripple" in German. | Krüppel means, literally, "cripple" in German. | ||
Put into English, it controls the development of a zygote early on in its growth, causing a gap in the otherwise [[heterogeneous]] arrangement of cells. It also controls access to several other subsequent genes, imposing order on the developing embryo.<ref>http://www.flybase.org/allied-data/lk/interactive-fly/segment/kruppel1.htm</ref> | Put into English, it controls the development of a zygote early on in its growth, causing a gap in the otherwise [[heterogeneous]] arrangement of cells. It also controls access to several other subsequent genes, imposing order on the developing embryo.<ref>[http://www.flybase.org/allied-data/lk/interactive-fly/segment/kruppel1.htm Interactive Fly, Drosophila<!-- Bot generated title -->]</ref> | ||
See also [[Kruppel-like factors]] which have been recently investigated in the heart but are well characterised for their role in carcinogenesis. | See also [[Kruppel-like factors]] which have been recently investigated in the heart but are well characterised for their role in carcinogenesis. | ||
Revision as of 04:29, 9 February 2008
Krüppel is a gap gene which encodes a zinc finger protein with four tandemly repeated zinc finger domains.[1]
Krüppel means, literally, "cripple" in German.
Put into English, it controls the development of a zygote early on in its growth, causing a gap in the otherwise heterogeneous arrangement of cells. It also controls access to several other subsequent genes, imposing order on the developing embryo.[2]
See also Kruppel-like factors which have been recently investigated in the heart but are well characterised for their role in carcinogenesis.
External links
- Diagram at Davidson College - a Drosophila embryo at the cellular blastoderm stage triple-labeled for three segmentation proteins including Krüppel (in blue) Hairy (green) and Giant (red).
References
External links
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