Jump to content

Insulin-like growth factor II IRES: Difference between revisions

From IdeaWazaWiki
wikademia>Wikademia
m 5 revisions
wikademia>Wikademia
mNo edit summary
Line 1: Line 1:
{{Orphan|date=February 2009}}
{{Rfam_box|acc=RF00483|description=Insulin-like growth factor II IRES|abbreviation=IRES_IGF2|type=Cis-reg; IRES;|avg_length=118.4|avg_identity=95|ss=Published; {{PMID|11903044}}|se=Moxon SJ|type=Cis-reg; IRES;}}
{{Rfam_box|acc=RF00483|description=Insulin-like growth factor II IRES|abbreviation=IRES_IGF2|type=Cis-reg; IRES;|avg_length=118.4|avg_identity=95|ss=Published; {{PMID|11903044}}|se=Moxon SJ|type=Cis-reg; IRES;}}


Line 8: Line 7:
{{reflist|1}}
{{reflist|1}}


==External links==
== External links ==


* {{Rfam|id=RF00483|name=Insulin-like growth factor II IRES}}
* {{Rfam|id=RF00483|name=Insulin-like growth factor II IRES}}

Revision as of 19:38, 21 March 2009

Insulin-like growth factor II IRES
Template:Abbreviation
Type: Cis-reg; IRES;
2° structure: Published; PubMed
Seed alignment: Moxon SJ
Avg length: 118.4 nucleotides
Avg identity: 95%

The insulin-like growth factor II (IGF-II) internal ribosome entry site IRES is found in the 5' UTR of IGF-II leader 2 mRNA. This RNA element allows cap-independent translation of the mRNA and it is thought that this family may facilitate a continuous IGF-II production in rapidly dividing cells during development.[1]

References

  1. ↑ Pedersen, SK; Christiansen J, Hansen TO, Larsen MR, Nielsen FC (2002). "Human insulin-like growth factor II leader 2 mediates internal initiation of translation". Biochem J 363: 37–44. doi:10.1042/0264-6021:3630037. PMID 11903044.