| Insulin-like growth factor II IRES
|
|
| Type:
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Cis-reg; IRES;
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| 2° structure:
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Published; PubMed
|
| Seed alignment:
|
Moxon SJ
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| Avg length:
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118.4 nucleotides
|
| Avg identity:
|
95%
|
|
The insulin-like growth factor II (IGF-II) internal ribosome entry site IRES is found in the 5' UTR of IGF-II leader 2 mRNA. This RNA element allows cap-independent translation of the mRNA and it is thought that this family may facilitate a continuous IGF-II production in rapidly dividing cells during development.[1]
References
- ↑ Pedersen, SK; Christiansen J, Hansen TO, Larsen MR, Nielsen FC (2002). "Human insulin-like growth factor II leader 2 mediates internal initiation of translation". Biochem J 363: 37–44. doi:10.1042/0264-6021:3630037. PMID 11903044.
External links
